Making Sense I. Introduction / theme / structure II. Language and meaning A. Reference and Platonism B. Use and Wittgenstein III. Mathematics A. Axiomatics and applicability B. Probability and information IV. Theories, models and simulation A. What is a theory ii. History and context, purposes / uses iii. Theories, models, instances, paradigms iv. Lenses v. Objects B. On building models V. Summary and conclusions